Search on: B 518 
Descriptors Found: 1
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Descriptor English:   Cyclophosphamide 
Descriptor Spanish:   Ciclofosfamida 
Descriptor Portuguese:   Ciclofosfamida 
Synonyms English:   B-518
Cyclophosphamide Anhydrous
Cyclophosphamide Monohydrate
Cyclophosphamide, (R)-Isomer
Cyclophosphamide, (S)-Isomer
Cyclophosphane
Cytophosphan
Cytophosphane
Cytoxan
Endoxan
NSC-26271
Neosar
Procytox
Sendoxan
Anhydrous, Cyclophosphamide
B 518
B518
Monohydrate, Cyclophosphamide
NSC 26271
NSC26271  
Tree Number:   D02.455.526.728.650.730.243
D02.705.672.500.243
Definition English:   Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the LIVER to form the active aldophosphamide. It has been used in the treatment of LYMPHOMA and LEUKEMIA. Its side effect, ALOPECIA, has been used for defleecing sheep. Cyclophosphamide may also cause sterility, birth defects, mutations, and cancer. 
Pharmacological Action:   Antineoplastic Agents, Alkylating
Antirheumatic Agents
Immunosuppressive Agents
Mutagens
Myeloablative Agonists
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   3540 
Unique Identifier:   D003520 

Occurrence in VHL:
 

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